Proteomic study of SUMOylation during Solanum tuberosum / Phytophthora infestans in (in-) compatible interactions


  • Colignon, B. , Dieu, M. , Demazy, C. , Delaive, E. , Muhovski, Y. , Raes, M. & Mauro, S. (2017). Proteomic study of SUMOylation during Solanum tuberosum / Phytophthora infestans in (in-) compatible interactions. Poster in: 4th Annual Conference of the COST Action-SUSTAIN, Bled, Slovenia, 1-3 March 2017.
Type Poster
Year 2017
Event name 4th Annual Conference of the COST Action-SUSTAIN
Event location Bled, Slovenia
Label U1- Mauro-2017
Event date 1-3 March 2017
Abstract Invasive plant pathogens have developed the ability to modify metabolic processes of their host and to promote those which facilitate their growth at the expense of the host. SUMOylation is widely conserved posttranslational modification in eukaryotic organisms, and this process exerts pleiotropic functional consequences that include changes in many aspects of protein activities, functions, stability, localization and interactions with other partners. Here we provide experimental evidence indicating that the SUMO pathway is partially under transcriptional control in Phythopthora infestans infected Solanum tuberosum leaves. We also report the results of using a recently developed proteomic approach based on the use of 3D gels to identify the endogenous SUMO targets and we show that during the infection process the abundance of most of these conjugates either increases, or decreases, significantly. This study primes further investigations into the molecular connections between host SUMOylation and Phythopthora infestans infection.
Authors Colignon, B. , Dieu, M. , Demazy, C. , Delaive, E. , Muhovski, Y. , Raes, M. & Mauro, S.