Proteomic study of SUMOylation during Solanum tuberosum / Phytophthora infestans interactions


  • Colignon, B. , Dieu, M. , Demazy, C. , Delaive, E. , Muhovski, Y. , Raes, M. & Mauro, S. (2017). Proteomic study of SUMOylation during Solanum tuberosum / Phytophthora infestans interactions. Mol Plant Microbe Interact, 30: (11), 855-865.
Type Journal Article
Year 2017
Journal Mol Plant Microbe Interact
Label U1-Mauro 2017
Volume 30
Issue 11
Pages 855-865
Date July 2017
Abstract Invasive plant pathogens have developed the ability to modify the metabolism of their host, promoting metabolic processes which facilitate the growth of the pathogen; at the general expense of the host. The particular enzymatic process SUMOylation which performs post-translational modification of target proteins, leading to changes in many aspects of protein activity and hence metabolism has been demonstrated to be active in many eukaryotic organisms, both animals and plants. Here we provide experimental evidence which indicates that in leaves of Solanum tuberosum which have been infected by Phytophthora infestans, the SUMO pathway enzymes of the host are partially under transcriptional control exerted by the oomycete. Using a recently-developed approach that employs 3D gels, we show here that during the infection process the abundance of most of the known SUMO conjugates of S. tuberosum changes significantly, some decreasing but many increasing in abundance. The new proteomic approach has the potential to greatly facilitate investigation of the molecular events that take place during the invasion by a pathogen of its host plant.
Lien doi: 10.1094/MPMI-05-17-0104-R
Authors Colignon, B. , Dieu, M. , Demazy, C. , Delaive, E. , Muhovski, Y. , Raes, M. & Mauro, S.